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CBD oil is being spotted more and more in health stores around the country, but how legal actually is it, and what does the future hold? Arkansas Marijuana - Home | Facebook Arkansas Marijuana. 1,333 likes. We will try and provide News and Information revolving around Marijuana within Arkansas & the Industry as a whole. Cannabidiol - Wikipedia Cannabidiol may be an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain. It also may act as an inverse agonist of GPR3, GPR6, and GPR12. CBD has been shown to act as a serotonin 5-HT 1A receptor partial agonist.